Translational Research in Maternal and Pediatric Pharmacology and Therapeutics (R21 Clinical Trial Optional)
OpenUpdated: Oct 30, 2025
Summary
The grant aims to support translational and clinical research that advances precision medicine for pregnant and lactating women, neonates, and children, focusing on developing novel tools and therapeutics to improve health outcomes. Eligible applicants include various government entities, educational institutions, for-profit and nonprofit organizations, and other specific groups such as tribal organizations and historically black colleges. Application details are not provided in the description; interested parties should refer to the full opportunity announcement for more information.
Full Description
Description
The purpose of this notice of funding opportunity (NOFO) is to support translational and clinical research to (1) advance precision medicine in pregnant women, lactating women, and children through the development of novel tools, models, and other technologies that could have a direct clinical or health impact; (2) enhance the understanding of the underlying mechanisms of drug action, including the role of pediatric ontogeny and the dynamic physiological changes that occur during pregnancy and lactation; and (3) discover and develop novel therapeutics or enhance the usage of existing drugs or drug repurposing for safer and more effective medications in pregnant and lactating women, neonates, and children. The overall goal is to improve safe and effective precision therapeutics for pregnant and lactating women, fetuses, neonates, and children, including those with disabilities.
Eligibility
Eligible applicants
Government
- State governments
- Federally recognized Native American tribal governments
- Public and Indian housing authorities
- City or township governments
- Special district governments
- County governments
Education
- Independent school districts
- Public and state institutions of higher education
- Private institutions of higher education
Business
- For-profit organizations other than small businesses
- Small businesses
Miscellaneous
- Other
Nonprofit
- Other Native American tribal organizations
- Nonprofits non-higher education without 501(c)(3)
- Nonprofits non-higher education with 501(c)(3)
Additional information
Grantor contact information
Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
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