Strategies to Improve Health Outcomes and Reduce Health Disparities in Rural Populations (R01 Clinical Trial Optional)
OpenUpdated: Oct 30, 2025
Summary
The grant aims to support research focused on developing, adapting, and evaluating interventions addressing social determinants of health (SDOH) to improve health outcomes and reduce health disparities in rural populations. Eligible applicants include nonprofits, educational institutions, government entities, and businesses, particularly those with a focus on rural health issues. Interested parties should prepare to apply as the funding opportunity will be published soon, and they can contact karen.kehl@nih.gov for more information.
Full Description
Description
The purpose of this notice is to inform the research community that the National Institute of Nursing Research (NINR) intends to publish a notice of funding opportunity (NOFO), Strategies to Improve Health Outcomes and Reduce Health Disparities in Rural Populations (R01 Clinical Trial Optional), a re-issuance of RFA-NR-24-005.
This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.
This NOFO will utilize the R01 activity code. Details of the planned NOFO are provided below.
Research Initiative Details
This funding opportunity will support research that seeks to develop, adapt, and/or evaluate social determinants of health (SDOH) interventions, or test strategies for the implementation of SDOH interventions already shown to be effective in rural populations. Research must address SDOH in the development, adaptation, implementation, or evaluation of interventions. Interventions or implementation strategies seeking to either mitigate or eliminate the impacts of adverse SDOH and/or bolster positive SDOH are of interest. Successful, evidence-based interventions may be adapted to specific rural communities and tested for acceptability and efficacy or effectiveness. Pragmatic and implementation studies are welcome, including hybrid effectiveness/implementation studies of adapted interventions or intervention bundles. Studies that include the evaluation of the impact of an event or policy (e.g., closing of local hospital, opening of a new employment center, change in internet access, new school consolidation) are welcome. Applications that are responsive to this NOFO will include an organizational-, community-, or population-level SDOH intervention. In addition, individual- or interpersonal-level interventions can be included in a multi-level intervention or intervention bundle.
Eligibility
Eligible applicants
Nonprofit
- Nonprofits non-higher education with 501(c)(3)
- Other Native American tribal organizations
Education
- Public and state institutions of higher education
- Independent school districts
- Private institutions of higher education
Government
- Public and Indian housing authorities
- County governments
- Federally recognized Native American tribal governments
- State governments
Business
- Small businesses
- For-profit organizations other than small businesses
Additional information
Grantor contact information
Description
karen.kehl@nih.gov
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