Grant Directory

Verified government funding opportunities

Small R01s for Clinical Trials Targeting Diseases within the Mission of NIDDK (R01 Clinical Trial Required)

Open

National Institutes of Health

Deadline: May 7, 2026federal

Updated: Oct 30, 2025

Summary

The grant aims to support pilot and feasibility clinical trials in humans that will provide preliminary data for larger trials focused on the prevention and treatment of diseases under the NIDDK's mission. Eligible applicants include private and public higher education institutions, government entities, nonprofits, small businesses, and various other organizations, with specific exclusions for non-domestic entities. Application details are not provided in the summary, but interested parties can contact NIH Grants Information for further inquiries.

Full Description

This Notice of Funding Announcement (NOFO) encourages the submission ofpilot and feasibilityclinical trialsconducted in humans that will lay the foundation for larger clinical trials related to the prevention and/or treatment of diseases and conditions within the mission of NIDDK. The program will support small, short-term proof-of-concept clinical trials in humans to acquire preliminary data regarding the effects of the intervention, as well as feasibility data related to recruitment and retention, and study conduct. Applications for clinical trials submitted under this NOFO should have clearly...

Eligibility

Eligible applicants

Education

  • Private institutions of higher education
  • Public and state institutions of higher education
  • Independent school districts

Government

  • Public and Indian housing authorities
  • Special district governments
  • State governments
  • City or township governments
  • Federally recognized Native American tribal governments
  • County governments

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Business

  • Small businesses
  • For-profit organizations other than small businesses

Miscellaneous

  • Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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