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Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

Open

National Institutes of Health

Deadline: federal

Updated: Oct 30, 2025

Summary

The Shared Instrumentation Grant (SIG) Program aims to support groups of NIH-supported investigators in purchasing or upgrading state-of-the-art instruments for shared use, enhancing research efficiency and collaboration. Eligible applicants include nonprofit organizations (with or without 501(c)(3) status) and both private and public institutions of higher education. To apply, interested parties should contact the grantor via email at xiang-ning.li@nih.gov for further details.

Full Description

Description

This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing shared-use instrumentation programs, i.e., the Shared Instrumentation Grant program, the High-End Instrumentation Grant program, and the Basic Instrumentation Grant program. The NOFO invites applications from groups of NIH-supported investigators to purchase or upgrade a single item of state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program require to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. The minimum award is $300,000. There is no cap on total cost of the instrument; however, the maximum award is $5,000,000. Cost sharing is required for premium instruments or special use instruments. 

Eligibility

Eligible applicants

Nonprofit

  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Education

  • Private institutions of higher education
  • Public and state institutions of higher education

Additional information

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Grantor contact information

Description

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Email

xiang-ning.li@nih.gov

xiang-ning.li@nih.gov

Apply on official siteUpdated Oct 30, 2025

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