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Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

Open

National Institutes of Health

Deadline: Jun 1, 2027federal

Updated: Oct 30, 2025

Summary

The Shared Instrument Grant (SIG) Program aims to support groups of NIH-supported investigators in purchasing or upgrading high-priced, specialized instruments, with awards ranging from $50,000 to $750,000. Eligible applicants include public and private institutions of higher education, various nonprofit organizations, and specific minority-serving institutions, while non-domestic entities are not eligible. Application details are not provided in the description; interested parties should refer to the full opportunity announcement for further information.

Full Description

Description

The Shared Instrument Grant (SIG) Program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-priced, specialized, commercially available instruments or integrated instrumentation system. The minimum award is $50,000. There is no maximum price limit for the instrument; however, the maximum award is $750,000. Instruments supported include, but are not limited to: light microscopes, biomedical imagers, mass spectrometers, nuclear magnetic resonance spectrometers, flow cytometers, DNA and protein sequencers, biosensors, and X-ray diffractometers.

Eligibility

Eligible applicants

Education

  • Public and state institutions of higher education
  • Private institutions of higher education

Nonprofit

  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)

Miscellaneous

  • Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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