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Schizophrenia and related disorders during mid- to late-life (R21 Clinical Trial Optional)

Open

National Institutes of Health

Deadline: Sep 7, 2026federal

Updated: Oct 30, 2025

Summary

The purpose of this grant is to advance translational research on the emergence and trajectory of schizophrenia and related disorders in mid to late life, aiming to identify targets for future prevention and treatment efforts. Eligible applicants include for-profit organizations, government entities, nonprofits, educational institutions, and various other organizations, including those serving specific communities. Application details are not provided in the description; interested parties should refer to the full opportunity announcement for further information.

Full Description

Description

Although the majority living with schizophrenia and related disorders are over 35 years old, including those first diagnosed and those aging with the illness, the mechanisms underlying the generation and trajectory of the illness remain poorly understood. The purpose of this initiative is to advance translational research to better understand the emergence and trajectory of schizophrenia and related disorders in mid to late life, and to identity targets for future development of prevention and treatment efforts.

Eligibility

Eligible applicants

Business

  • For-profit organizations other than small businesses
  • Small businesses

Government

  • County governments
  • Federally recognized Native American tribal governments
  • City or township governments
  • State governments
  • Public and Indian housing authorities
  • Special district governments

Nonprofit

  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)
  • Other Native American tribal organizations

Education

  • Private institutions of higher education
  • Independent school districts
  • Public and state institutions of higher education

Miscellaneous

  • Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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