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Role of Defective Proviruses in HIV Persistence (R01 Clinical Trial Not Allowed)

Open

National Institutes of Health

Deadline: Jan 7, 2028federal

Updated: Oct 30, 2025

Summary

The grant aims to support research on the impact of defective HIV proviruses on HIV persistence and pathogenesis during antiretroviral treatment, as well as their effects on HIV cure strategies and molecular assays. Eligible applicants include various government entities, nonprofits, educational institutions, and for-profit organizations, including small businesses and specific minority-serving institutions. Application details are not provided in the description; for further inquiries, applicants can contact NIH Grants Information at grantsinfo@nih.gov.

Full Description

The purpose of this notice of funding opportunity (NOFO) is to support research to define the impact of defective HIV proviruses on mechanisms of HIV persistence and pathogenesis during antiretroviral treatment and their potential deleterious effects on HIV cure strategies and interference with HIV-specific molecular assays.

Eligibility

Eligible applicants

Government

  • Public and Indian housing authorities
  • Special district governments
  • State governments
  • City or township governments
  • Federally recognized Native American tribal governments
  • County governments

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Education

  • Private institutions of higher education
  • Independent school districts
  • Public and state institutions of higher education

Miscellaneous

  • Other

Business

  • For-profit organizations other than small businesses
  • Small businesses

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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