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Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R01 Clinical Trial Optional)

Open

National Institutes of Health

Deadline: Sep 7, 2026federal

Updated: Oct 30, 2025

Summary

The grant aims to support studies that enhance understanding of neuropsychiatric symptoms in individuals with Alzheimer's disease and related dementias, potentially leading to new therapeutic interventions. Eligible applicants include various government entities, educational institutions, small and for-profit businesses, and nonprofit organizations, among others. Application details are not specified in the provided description; interested parties should refer to the full opportunity announcement for further information.

Full Description

The goal of this Funding Opportunity Announcement (FOA) is to encourage applications for studies that will enhance knowledge of mechanisms associated with neuropsychiatric symptoms (NPS) in persons with Alzheimer's disease (AD) or Alzheimer's disease-related dementias (ADRD). The findings are expected to advance mechanistic understanding of both biobehavioral and neurobiological pathways leading to NPS. Findings may also provide insight into novel therapeutic targets that can be advanced into interventions to treat and prevent the development of NPS in AD and/or ADRD

Eligibility

Eligible applicants

Government

  • Federally recognized Native American tribal governments
  • Special district governments
  • Public and Indian housing authorities
  • County governments
  • City or township governments
  • State governments

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Business

  • Small businesses
  • For-profit organizations other than small businesses

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Miscellaneous

  • Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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