Grant Directory

Verified government funding opportunities

NINDS Renewal Awards of SBIR Phase II Grants (Phase IIB) for Pre-Clinical Research (R44 Clinical Trial Not Allowed)

Open

National Institutes of Health

Deadline: Apr 5, 2027federal

Updated: Oct 30, 2025

Summary

The grant aims to assist small businesses that have previously received SBIR or STTR Phase II funding in bridging the funding gap to achieve commercialization of medical biotechnology products. Eligible applicants are small businesses, while non-domestic entities and foreign components of U.S. organizations are not eligible. Applicants are encouraged to secure independent third-party funding during the project period, and further details can be obtained by contacting NIH Grants Information at grantsinfo@nih.gov.

Full Description

Some projects initiated with SBIR or STTR funding require considerable financing beyond the SBIR/STTR Phase II award to achieve commercialization. The development of medical biotechnology products is often impeded by a significant funding gap (known as the Valley of Death) between the end of the SBIR/STTR Phase II award and the commercialization stage. The goal of this FOA is to assist applicants in pursuing the next appropriate milestone(s) necessary to advance a product/technology that requires Federal regulatory approval or to bring a complex research tool to market. This opportunity aims to...

Eligibility

Eligible applicants

Business

  • Small businesses

Additional information

Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

Recommended Resource

Grant Writing Services on Fiverr

Top Pick

Struggling with grant applications? Get expert help from professional freelance writers on Fiverr — from research and proposal drafts to compliance review and submission. Secure funding faster with proven talent.