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NINDS Exploratory Clinical Trials for Small Business (R43/R44 Clinical Trial Required)

National Institutes of Health

Deadline: Sep 5, 2026

Summary

The purpose of this grant is to support Small Business Concerns (SBCs) in submitting Small Business Innovation Research (SBIR) applications for investigator-initiated exploratory clinical trials related to the mission of the National Institute of Neurological Disorders and Stroke (NINDS). Eligible applicants are small businesses, with only SBIR Phase II and Fast-Track applications being accepted; Phase I applications are only permitted as part of a Fast-Track application. For application details, refer to the full opportunity announcement and contact NIH Grants Information for further inquiries.

Full description

Description

(Reissue of PAR-21-266) The purpose of this funding opportunity announcement (FOA) is to provide a vehicle for Small Business Concerns (SBCs) submitting Small Business Innovation Research (SBIR) grant applications for investigator-initiated exploratory clinical trials to the National Institute of Neurological Disorders and Stroke (NINDS). The projects must focus on products related to the mission and goals of the NINDS and may evaluate drugs, biologics, devices, or diagnostics, as well as surgical, behavioral or rehabilitation therapies. Only SBIR Phase II and Fast-Track applications are supported under this program. SBIR Phase I applications are only accepted as part of a Fast-track application.

Eligibility

Eligible applicants

Business

  • Small businesses

Additional information

Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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