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NINDS Efficacy and Exploratory Clinical Trials (UG3/UH3 - Clinical Trial Required)

Open

National Institutes of Health

Deadline: federal

Updated: Oct 30, 2025

Summary

The National Institute of Neurological Disorders and Stroke (NINDS) is preparing to publish a Notice of Funding Opportunity (NOFO) for research on exploratory and efficacy clinical trials related to its mission, focusing on various therapies and interventions. Eligible applicants include public and private educational institutions, government entities, for-profit and nonprofit organizations, and other specified groups. While applications are not currently being accepted, potential applicants are encouraged to start developing collaborations and projects in anticipation of the NOFO release; further inquiries can be directed to Exploratory_Efficacy_Trials@ninds.nih.gov.

Full Description

Description

The National Institute of Neurological Disorders and Stroke (NINDS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research on exploratory and efficacy clinical trials that address questions within the mission and research interests of the NINDS and may evaluate drugs, biologics, and devices, as well as surgical, behavioral and rehabilitation therapies.  Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the UG3/UH3 activity code. Investigators with expertise and insights into the mission and research interests of the NINDS, found at the NINDS website (https://www.ninds.nih.gov/), are encouraged to begin to consider applying for this new NOFO. 

Eligibility

Eligible applicants

Miscellaneous

  • Other

Education

  • Public and state institutions of higher education
  • Independent school districts
  • Private institutions of higher education

Government

  • City or township governments
  • County governments
  • Special district governments
  • Federally recognized Native American tribal governments
  • Public and Indian housing authorities
  • State governments

Business

  • For-profit organizations other than small businesses
  • Small businesses

Nonprofit

  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)
  • Other Native American tribal organizations

Additional information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Grantor contact information

Description

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Email

Exploratory_Efficacy_Trials@ninds.nih.gov

Exploratory_Efficacy_Trials@ninds.nih.gov

Apply on official siteUpdated Oct 30, 2025

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