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NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)

Open

National Institutes of Health

Deadline: Jan 7, 2028federal

Updated: Oct 30, 2025

Summary

The NIH Research Project Grant aims to support specific research projects aligned with the interests of participating NIH Institutes and Centers, excluding clinical trial proposals. Eligible applicants include various government entities, educational institutions, nonprofits, small businesses, and other organizations, including those serving Native American populations and historically underrepresented groups. To apply, interested parties should refer to the full opportunity announcement for detailed application instructions.

Full Description

Description

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. This Notice of Funding Opportunity does not accept applications proposing clinical trial(s).

Eligibility

Eligible applicants

Government

  • State governments
  • Special district governments
  • City or township governments
  • County governments
  • Federally recognized Native American tribal governments
  • Public and Indian housing authorities

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Business

  • Small businesses
  • For-profit organizations other than small businesses

Miscellaneous

  • Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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