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Verified government funding opportunities

NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)

Open

National Institutes of Health

Deadline: Feb 26, 2027federal

Updated: Oct 30, 2025

Summary

The Small Business Innovation Research (SBIR) Program aims to support the development of innovative solutions for public health challenges, specifically targeting later-stage research and development (Phase IIB) for projects addressing rare diseases or young pediatric populations. Eligible applicants are small businesses that have previously received SBIR or STTR Phase II awards; non-domestic entities are not eligible. To apply, interested small businesses should submit their grant applications as outlined in the Notice of Funding Opportunity.

Full Description

The Small Business Innovation Research (SBIR) Program is an important National Institutes of Health (NIH) funding mechanism used to develop innovative solutions that address public health challenges. A major objective of the SBIR Program is to facilitate the commercialization of technologies developed by small business concerns (SBCs). Yet, the development of biomedical products is often impeded by a significant funding gap between the end of the SBIR Phase II award and the commercialization stage. This gap is increased by the barriers associated with technologies under development for small commercial...

Eligibility

Eligible applicants

Business

  • Small businesses

Additional information

Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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