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National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)

Open

National Institutes of Health

Deadline: Jan 7, 2027federal

Updated: Oct 30, 2025

Summary

The grant aims to fund early phase investigator-initiated clinical trials focused on cancer-targeted diagnostic and therapeutic interventions relevant to specific research programs of the National Cancer Institute. Eligible applicants include for-profit organizations, nonprofits, government entities, educational institutions, and various other organizations, including those serving Native American populations. Application details are not specified in the provided text; interested parties should refer to the full opportunity announcement for more information.

Full Description

Through this Notice of Funding Opportunity, the National Cancer Institute (NCI) seeks research projects that implement early phase (Phase 0, I, and II) investigator-initiated clinical trials focused on cancer-targeted diagnostic and therapeutic interventions of direct relevance to the research mission of DCTD and OHAM. The proposed project must involve at least 1 clinical trial related to the scientific interests of one or more of the following research programs: Cancer Therapy Evaluation Program, Cancer Imaging Program, Cancer Diagnosis Program, Radiation Research Program, Complementary and...

Eligibility

Eligible applicants

Business

  • For-profit organizations other than small businesses
  • Small businesses

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)

Government

  • County governments
  • City or township governments
  • State governments
  • Special district governments
  • Public and Indian housing authorities
  • Federally recognized Native American tribal governments

Miscellaneous

  • Other

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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