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Mitochondrial-associated Mechanisms of Neuropathological and Immunodeficient Aging in the Context of HIV and SUD (R01 Clinical Trials Not Allowed)

Open

National Institutes of Health

Deadline: Mar 10, 2026federal

Updated: Oct 30, 2025

Summary

The grant aims to promote research on the protective and pathogenic mechanisms related to mitochondrial function and aging in the context of HIV infection and substance use, with the goal of developing targeted therapies to improve outcomes for aging individuals with HIV and addiction. Eligible applicants include independent school districts, public and private higher education institutions, various levels of government, nonprofits, small businesses, and other organizations, including those serving specific communities such as Native Americans and historically underrepresented groups. Application details are not provided in the description; interested parties should refer to the full opportunity announcement for more information.

Full Description

Description

To promote research investigating protective and pathogenic mechanisms at the nexus of mitochondria function and aging in the context of HIV infection and exposure to addictive substances. We anticipate this foundational knowledge could be leveraged to develop targeted therapies and improve outcomes in people aging with HIV, substance use and addiction.

Eligibility

Eligible applicants

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Government

  • County governments
  • State governments
  • Special district governments
  • City or township governments
  • Public and Indian housing authorities
  • Federally recognized Native American tribal governments

Nonprofit

  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)
  • Other Native American tribal organizations

Miscellaneous

  • Other

Business

  • Small businesses
  • For-profit organizations other than small businesses

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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