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Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)

Open

National Institutes of Health

Deadline: Oct 19, 2026federal

Updated: Oct 30, 2025

Summary

The purpose of this grant is to support NCATS CTSA Program KL2 scholars and re-entry supplement recipients in conducting clinical and translational research projects, including pilot studies and methodology development, to aid their transition to independent academic scientists. Eligible applicants include various nonprofit organizations, educational institutions, government entities, and small businesses, with specific provisions for certain minority-serving institutions. Application details are not provided in the summary, but interested parties can contact NIH Grants Information for further inquiries.

Full Description

The purpose of this NOFO is to enhance the capability of NCATS CTSA Program KL2 scholars and recipients of re-entry supplements supported by the CTSA Program to conduct research as they complete the transition to fully independent academic translational scientists. These R03 grants will support different clinical and translational science research projects, including pilot and feasibility studies; secondary data analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. Research proposed in the R03 application may or may not include patient-oriented research. The R03 is, therefore, intended to support research projects that can be carried out in a short period of time with limited resources and that provide preliminary data to support submission of a subsequent R01, or equivalent, application.

Eligibility

Eligible applicants

Nonprofit

  • Nonprofits non-higher education without 501(c)(3)
  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Government

  • City or township governments
  • Public and Indian housing authorities
  • State governments
  • County governments
  • Federally recognized Native American tribal governments
  • Special district governments

Business

  • Small businesses
  • For-profit organizations other than small businesses

Miscellaneous

  • Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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