Limited Competition: Outcomes of Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network - Clinical Sites (U01, Clinical Trial Required)
OpenUpdated: Oct 30, 2025
Summary
The National Human Genome Research Institute (NHGRI) is offering a grant to extend follow-up and collect outcome data for participants in the eMERGE Network who receive genomically informed risk assessment and management recommendations. Eligible applicants include public and private higher education institutions and nonprofits with 501(c)(3) status, specifically those funded under previous RFAs (RFA-HG-19-013 and RFA-HG-19-014). The Notice of Funding Opportunity (NOFO) is expected to be published in 2025, with applications due later that year.
Full Description
Description
The National Human Genome Research Institute (NHGRI) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications for research to extend follow-up and collection of outcome data for the 25,000 participants receiving genomically informed risk assessment (GIRA) and management recommendations in the Electronic Medical Records and Genomics (eMERGE) Network. This multi-site continuation of the eMERGE Genomic Risk Assessment and Management Study will: 1) extend follow-up of eMERGE participants from a minimum 1 year to at least 4 years; 2) assess longer-term adherence to and outcomes of GIRA-based preventative recommendations among clinicians and participants; and 3) identify correlates of adherence by condition, participant age and demographics, and other non-genomic factors. We plan to issue an RFA for the coordinating center as a single source and the clinical sites as a limited competition.
This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in 2025 with an expected application due date in 2025. This NOFO will utilize the U01 activity code.
Eligibility
Eligible applicants
Education
- Public and state institutions of higher education
- Private institutions of higher education
Miscellaneous
- Other
Nonprofit
- Nonprofits non-higher education with 501(c)(3)
Additional information
Grantor contact information
Description
Robb.Rowley@nih.gov
Recommended Resource
Grant Writing Services on Fiverr
Top PickStruggling with grant applications? Get expert help from professional freelance writers on Fiverr — from research and proposal drafts to compliance review and submission. Secure funding faster with proven talent.