Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Women, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional)
OpenUpdated: Oct 30, 2025
Summary
The purpose of this grant is to utilize NICHD clinical research Network infrastructure to conduct innovative, multisite, investigator-initiated clinical trials and observational studies focused on infants, children, women, pregnant and lactating women, and persons with disabilities. Eligible applicants include state and local governments, educational institutions, for-profit and nonprofit organizations, and various community-based organizations, among others. Applications must be submitted as multi-Project Director/Principal Investigator grant applications in collaboration with a NICHD-supported Network Data Coordinating Center.
Full Description
Description
The purpose of this Notice of Funding Opportunity (NOFO) is to leverage NICHD clinical research Network infrastructure relevant to infants, children, women, pregnant and lactating women, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. This NOFO will utilize a bi-phasic (UG3/UH3), milestone-driven mechanism consisting of a start-up phase (UG3) and a full enrollment and clinical trial implementation phase (UH3). Applications submitted in response to this NOFO must address specific aims and milestones for both the UG3 and UH3 phases. A UG3 project (phase I) that meets its milestones will be administratively considered by NICHD and prioritized for transition to the UH3 award (phase II). This NOFO provides an opportunity to leverage NICHD clinical research Network infrastructure as a platform for investigator-initiated innovative hypotheses by any investigator in the extramural community. Applications must be submitted as investigator-initiated, multi-Project Director/Principal Investigator (PD/PI) grant applications in conjunction with the respective NICHD-supported Network Data Coordinating Center (DCC), or equivalent as determined by the NICHD.
Eligibility
Eligible applicants
Government
- State governments
- Federally recognized Native American tribal governments
- Public and Indian housing authorities
- City or township governments
- Special district governments
- County governments
Education
- Independent school districts
- Public and state institutions of higher education
- Private institutions of higher education
Business
- For-profit organizations other than small businesses
- Small businesses
Miscellaneous
- Other
Nonprofit
- Other Native American tribal organizations
- Nonprofits non-higher education without 501(c)(3)
- Nonprofits non-higher education with 501(c)(3)
Additional information
Grantor contact information
Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
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