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Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)

Open

National Institutes of Health

Deadline: Oct 20, 2027federal

Updated: Oct 30, 2025

Summary

The grant aims to support research applications focused on developing in vitro and ex vivo assays to identify therapeutic agents for neurological or neuromuscular disorders, as part of the Innovation Grants to Nurture Initial Translational Efforts (IGNITE) initiative. Eligible applicants include various nonprofit organizations, government entities, educational institutions, for-profit organizations, and other specified groups such as tribal governments and minority-serving institutions. Application details can be found in the full opportunity announcement, and inquiries can be directed to NIH Grants Information at grantsinfo@nih.gov.

Full Description

Description

This funding opportunity announcement (FOA) encourages research grant applications to develop in vitro and/or ex vivo assays and conduct iterative screening efforts to identify and characterize potential therapeutic agents for neurological or neuromuscular disorders. This FOA is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) to advance projects to the point where they can meet the entry criteria for the Blueprint Neurotherapeutics Network (BPN) or other translational programs.

Eligibility

Eligible applicants

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Government

  • County governments
  • State governments
  • Public and Indian housing authorities
  • Federally recognized Native American tribal governments
  • Special district governments
  • City or township governments

Education

  • Private institutions of higher education
  • Public and state institutions of higher education
  • Independent school districts

Business

  • For-profit organizations other than small businesses
  • Small businesses

Miscellaneous

  • Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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