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High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)

Open

National Institutes of Health

Deadline: Jun 1, 2027federal

Updated: Oct 30, 2025

Summary

The High-End Instrumentation (HEI) Grant Program aims to support NIH-supported investigators in purchasing or upgrading high-end, specialized instruments, with awards ranging from $750,001 to $2,000,000. Eligible applicants include public and private institutions of higher education, various nonprofit organizations, and specific minority-serving institutions, while non-domestic entities are not eligible. To apply, interested parties should refer to the full opportunity announcement for detailed application instructions.

Full Description

The High-End Instrumentation (HEI) Grant Program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-end, specialized, commercially available instruments or integrated systems. The minimum award is $750,001. There is no maximum price limit for the instrument; however, the maximum award is $2,000,000. Instruments supported include, but are not limited to, nuclear magnetic resonance spectrometers, X-ray diffractometers, mass spectrometers, high throughput robotic screening systems, DNA and protein sequencers, biosensors, electron and light microscopes, flow cytometers, and biomedical imagers.

Eligibility

Eligible applicants

Education

  • Public and state institutions of higher education
  • Private institutions of higher education

Miscellaneous

  • Other

Nonprofit

  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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