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HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)

Open

National Institutes of Health

Deadline: Nov 23, 2026federal

Updated: Oct 30, 2025

Summary

The grant aims to support R15-eligible Principal Investigators in conducting basic and mechanistic pain research, foster interdisciplinary partnerships, and enhance the research environment for health professional trainees and students. Eligible applicants include private and public institutions of higher education, as well as specific minority-serving institutions, while non-domestic entities are not eligible. Application details are not provided in the description; interested parties should refer to the full opportunity announcement for more information.

Full Description

The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects.

Eligibility

Eligible applicants

Education

  • Private institutions of higher education
  • Public and state institutions of higher education

Miscellaneous

  • Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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