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Forecast to Publish a Notice of Funding Opportunity for Small Business Transition Grant For Early Career Scientists (R41/R42 Clinical Trial Not Allowed)

Open

National Institutes of Health

Deadline: federal

Updated: Oct 30, 2025

Summary

The grant aims to support early-career academic scientists in transitioning to entrepreneurship and facilitate the transfer of technology from academic labs to small businesses, addressing challenges in team formation and funding for early-stage development. Eligible applicants include government entities, educational institutions, nonprofits, and small businesses. Applications are not currently being accepted, but a Notice of Funding Opportunity (NOFO) is expected to be published in Summer 2025, with applications due in Fall 2025.

Full Description

Description

The National Cancer Institute (NCI), with National Human Genome Research Institute (NHGRI) and National Institute of Biomedical Imaging and Bioengineering (NIBIB), intends to publish a Notice of Funding Opportunity (NOFO) to support early-career academic scientists interested in transitioning to entrepreneurship while also supporting the transfer of technology from academic laboratories into small businesses. Both small businesses and universities are drivers of technological innovation in the United States (U.S.), often working together to advance innovative ideas into products that can benefit the U.S. population. While most NIH funding supports basic research in university laboratories, the NIH also supports innovative technology development in U.S. small businesses through its SBIR and STTR programs. As technologies transition from academic discovery to small businesses, two common challenges arise, identifying the right team with the right expertise to take the product into a small business, and funding for early-stage technology development. This NOFO seeks to address both challenges simultaneously by having two equally important goals: entrepreneurial mentoring support, and product development support.


Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R41/R42 activity code. The NOFO is expected to be published in Summer 2025 with an anticipated application due date in Fall 2025.

Eligibility

Eligible applicants

Government

  • County governments
  • State governments
  • Federally recognized Native American tribal governments
  • Public and Indian housing authorities

Education

  • Public and state institutions of higher education
  • Private institutions of higher education
  • Independent school districts

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)

Business

  • Small businesses
  • For-profit organizations other than small businesses

Additional information

Grantor contact information

Description

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Email

saroj.regmi@nih.gov

saroj.regmi@nih.gov

Apply on official siteUpdated Oct 30, 2025

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