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Verified government funding opportunities

Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)

Open

National Institutes of Health

Deadline: Jan 7, 2028federal

Updated: Oct 30, 2025

Summary

The purpose of this grant is to support the discovery and early evaluation of candidate biomarkers and biomarker signatures for neurological and neuromuscular disorders, facilitating the clinical development of neurotherapeutics. Eligible applicants include various government entities, nonprofit organizations, educational institutions, and small businesses, with specific provisions for certain minority-serving institutions. Application details are not provided in the description, but interested parties can contact NIH Grants Information for further inquiries.

Full Description

The overarching purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery and/or early evaluation of strong candidate biomarkers and biomarker signatures that can be used as tools to facilitate the clinical development of neurotherapeutics and their use in clinical practice. Specifically, the focus of this FOA is on the identification and initial biological, analytical and clinical evaluation of biomarkers and biomarker signatures for neurological and neuromuscular disorders. Although research supported by this FOA can include animal studies, it must also include preliminary...

Eligibility

Eligible applicants

Government

  • City or township governments
  • Public and Indian housing authorities
  • Federally recognized Native American tribal governments
  • Special district governments
  • State governments
  • County governments

Miscellaneous

  • Other

Nonprofit

  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)
  • Other Native American tribal organizations

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Business

  • Small businesses
  • For-profit organizations other than small businesses

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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