Consortia for Structure-based Immunogen Design for HIV (CSID-HIV)
OpenUpdated: Oct 30, 2025
Summary
The grant from the National Institute of Allergy and Infectious Diseases (NIAID) aims to support research in structure-based immunogen design to develop HIV immunogens that induce broadly neutralizing antibody (bNAb) responses, facilitating their clinical testing and advancing vaccine development. Eligible applicants include public and private higher education institutions, government entities, for-profit and nonprofit organizations, and various other groups, including Native American tribal governments. Application details are not specified, but interested parties can contact the grantor via email at sshapiro@niaid.nih.gov for further information.
Full Description
Description
The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the National Institutes of Health (NIH) mission by supporting research to support structure-based immunogen design to advance the development and selection of HIV immunogens that induce broadly neutralizing antibody (bNAb) responses. These immunogens will then be advanced into clinical testing. Consortium research should address critical immunogen design roadblocks in discovering and developing safe and effective HIV bNAbs and bNAb responses that can be used as therapeutics, as well as guide vaccine development that could be used for both HIV treatment and prevention. This notice of funding opportunity (NOFO) will support coordinated multidisciplinary efforts on bNAb and vaccine discovery and applied research, emphasizing iterative approaches to expedite HIV therapeutics and vaccine development. The ultimate goal is to achieve proof of concept of therapeutic strategies using bNABs and vaccine-induction of bNAbs targeting multiple bNAb sites, while also integrating other cooperative immune responses. The technology being developed through these consortia will be applicable to other fields facing significant hurdles in viral antigen therapeutic targeting and vaccine design. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Eligibility
Eligible applicants
Education
- Public and state institutions of higher education
- Private institutions of higher education
- Independent school districts
Government
- Public and Indian housing authorities
- City or township governments
- County governments
- Special district governments
- State governments
- Federally recognized Native American tribal governments
Business
- For-profit organizations other than small businesses
- Small businesses
Nonprofit
- Nonprofits non-higher education with 501(c)(3)
- Nonprofits non-higher education without 501(c)(3)
- Other Native American tribal organizations
Miscellaneous
- Other
Additional information
Grantor contact information
Description
sshapiro@niaid.nih.gov
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