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Chemical Screening and Optimization Facility (X01 Clinical Trial Not Allowed)

Open

National Institutes of Health

Deadline: Apr 3, 2026federal

Updated: Oct 30, 2025

Summary

The grant aims to support the development of non-hormonal contraceptives and reproductive health products through preclinical services at the NICHD's Chemical Synthesis and Optimization Facility. Eligible applicants include government entities, nonprofits, for-profit organizations, educational institutions, and various other organizations, including those serving specific communities. To apply, interested parties should refer to the full opportunity announcement for detailed application instructions.

Full Description

The NICHD has a state-of-the-art Chemical Synthesis and Optimization Facility for advancing both non-hormonal contraceptive and reproductive health related product development. This facility has the capabilities and capacity for preclinical services including Investigational Device Exemption (IDE) or Investigational New Drug (IND)-enabling studies (e.g., protein generation, X-ray crystallography, high throughput screening, structure activity relationships, hit-to-lead generation, drug metabolism). The long-term objective is to enable a preclinical candidate for IND/IDE study(ies) that offers a safe...

Eligibility

Eligible applicants

Government

  • City or township governments
  • Special district governments
  • Federally recognized Native American tribal governments
  • County governments
  • State governments
  • Public and Indian housing authorities

Nonprofit

  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)
  • Other Native American tribal organizations

Business

  • For-profit organizations other than small businesses
  • Small businesses

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Miscellaneous

  • Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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