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CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed)

Open

National Institutes of Health

Deadline: Oct 16, 2026federal

Updated: Oct 30, 2025

Summary

The grant aims to support basic research projects focused on chemical warfare agents, toxic industrial chemicals, and pesticides that affect the nervous system, with the goal of generating data on toxicity mechanisms and potential therapeutic targets. Eligible applicants include various government entities, nonprofits, for-profit organizations, educational institutions, and specific tribal organizations, while non-domestic entities are not eligible. To apply, interested parties should refer to the full opportunity announcement for detailed application instructions.

Full Description

This announcement invites applications for basic research projects on chemical warfare agents, toxic industrial chemicals, and pesticides that have primary or secondary effects on the nervous system. Chemical threats are toxic compounds that could be used in a terrorist attack or accidentally released from industrial production, storage, or shipping. Projects supported by this NOFO are expected to generate data that elucidate mechanisms of toxicity of these agents, possible new manifestations of toxic exposures, and potential new targets for therapeutic development.

Eligibility

Eligible applicants

Government

  • Special district governments
  • City or township governments
  • Public and Indian housing authorities
  • County governments
  • State governments
  • Federally recognized Native American tribal governments

Nonprofit

  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)
  • Other Native American tribal organizations

Miscellaneous

  • Other

Business

  • For-profit organizations other than small businesses
  • Small businesses

Education

  • Public and state institutions of higher education
  • Private institutions of higher education
  • Independent school districts

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Apply on official siteUpdated Oct 30, 2025

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