The National Institute on Drug Abuse (NIDA), with other NIH Institutes and Centers (ICs), intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the research sites for the Adolescent Brain Cognitive Development (ABCD) Study. The ABCD study is the largest long-term study of brain development and child and adolescent health in the United States. This renewal will continue to follow the ABCD cohort into adulthood, when many of the outcomes of interest (e.g., substance use disorders, mental health disorders, chronic diseases, and other health conditions) will manifest. The ABCD Study has been highly successful in recruiting a cohort of almost 12,000 participants beginning at ages 9-10 and assessing them to ages 19-20. This proposed renewal would follow these children through their emerging adulthood until 26-27 years of age. By using cutting-edge technology such as brain scans and wearable sensors, scientists have an unprecedented opportunity to determine how young adult experiences (such as physical activity, healthy lifestyles, new technological habits like videogames or social media, and other Making America Health Again priority areas) interact with each other and with a young adult’s changing biology to affect brain development and social, behavioral, academic, health, and other outcomes. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U01 activity code. 

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